Blood coagulation is an important factor in making sure that after a certain blood loss in the body, clots are formed that further help in making sure that no blood loss occurs. The coagulation factor IX that is present in the body, also known as Christmas factor is produced as a precursor that is inactive, known as zymogen. Lack of this factor causes haemophilia of type B, and it is specifically processed to remove signal peptide, and form a 2 chain factor. This chain that is made of disulphide bonds and interacts with factor 8 and other molecules to completely help in clotting procedure.

Associated important factors:

As per tests that have been provided by Mouse coagulation factor IX (FIX) Elisa Kit, it has been found that this factor acts as a instigating aspect regarding zymogen. With help from this, further issues are taken into consideration. Also, there have been a number of diseases that are supposed reactions of this as detected by test results.

Apart from coagulation factor IX, other factors such as 7 and 10 also play a very important role in blood clotting, and hence share the structure associated with similar domain. Apart from general blood clotting, a deficiency in coagulation factor IX can cause some permanent bleeding disorders.