NADH Dehydrogenase, Quinone 1 is a specific enzyme that is encoded within NQO1 gene within the human body. Being homodimers, they are performers of dual electron reductase, and have an important part in redox dyes. Most importantly, it has a preference in case of acceptor quinones of short types such as juglon, duroquinone. This protein is specifically located in cytosol. In this enzyme in itself several structures are available, which make an important part of respiratory chain. The various subunits of this are part of the responsibility of translocation of protons.

There are chances of mutation in this gene, that have been strictly associated with dyskinesia of tardive type, also, there is an increase in risk of hematoxicity that would expose a person to benzene that could make a person susceptible to cancer.

There have been a number of tests that have been conducted with help of Mouse NADHDehydrogenase, Quinone 1 (NQO1) ELISA Kit which shows multiple functions that are associated with this. This includes breaking down of quinones from hydroquinones, prevents a singular reduction of electrons to quinones and further results in production of radical species. With increase in p53, there has been a resistance to drugs such as chemotherapeutics, which could have long term effects.