Cell adhesion molecules that are specifically prevalent in endothelial cells of human body have quite a role to play in regards to inflammation that occurs in human body. The Human soluble E-selectin is a specific type of antigen that belongs to a family member of E type, and is an important part of endothelial cell adhesion molecule 2 type. Coded within the SELE gene, this Human soluble E-selectin has a regular role in humans, and is primarily expressed only within endothelial cells that are activated by help of cytokines. Thus, this cytokine becomes a stimulator for the selectin type of initiator.

One can also specifically term them as chimeric proteins that have certain targeted regions, which has been specifically designed as antibody type properties. The immunoadhesin properties that are present are useful in decreasing attachment of leucocytes and hence can be used in certain cases as anti-inflammatory types of medication.

Benefits and usages of Human soluble E-selectin:

This specifically has a number of uses as regulation of genetic issues and attaches itself to ligands. This is further expressed by means of neutrophils, eosinophils, cytokines and lymphocytes that are acute and inflammatory in nature. Thus, one can surely state that it has a very important role in regards to inflammation wherein it recruits leucocytes in that site where injury has happened. Also, cancer cells can primarily infiltrate to those domains that are inflamed from the very beginning. This also has pathological influence in the form of coronary syndrome, pathogen attachment and as a biomarker. Further research is being carried on by Human soluble E-selectin,sE-selectin ELISA Kit.