Basic Information

Clenbuterol is a kind of asthma drugs. This drug is neither veterinary drugs, nor feed additives, but adrenergic nerve stimulants. Clarithromycin Hydrochloride; Clarithromycin Hydrochloride; Amlodipine; Ampivadine; Clenbuterol is well absorbed in livestock and humans, and its bioavailability is high compared to other beta-agonists, and human consumption of clenbuterol-containing pork is toxic.

Clenbuterol is a moderate accumulation of drugs in animal tissue accumulation and its dose and duration of administration, the residue with the extension of the withdrawal period gradually decreased. A large number of experiments have shown that clenbuterol residues in animals mainly concentrated in the eyes, hair, lung, liver, kidney and muscle and adipose tissue. The retina and choroid of the eye, the highest residue in hair, because the elimination of the slowest; followed by lung, liver and kidney; muscle tissue and adipose tissue residues roughly the same, about 1/5 of the liver. Clenbuterol residues in the lung and liver are generally higher than the kidney, and the residual time is longer.

Functions and uses

Clenbuterol is a β2 agonist, belongs to pseudo adrenergic drugs, trade name "ammonia", "astringent hormone". In the early 80s, a US company accidentally discovered that clenbuterol can significantly promote animal growth, and increase the lean rate. It can change the metabolic pathways in animal body, promote the synthesis of protein in muscle, especially skeletal muscle, inhibit the synthesis of fat, accelerate the growth speed, increase lean meat and improve carcass quality. This new discovery will soon be some countries for aquaculture, feed added clenbuterol hydrochloride, can make pigs and other livestock growth rate, feed conversion rate, carcass lean meat rate increased by 10% or more. So hydrochloric acid grams lentenol as a feed additive in the sale of the trade name, also known as "lean meat", "meat and more elements" and so on.

haxards summarizing

Adverse reactions:   clenbuterol can slow down the skeletal muscle fibers on the β receptor, so that accelerated contraction, manifested as hand can not hold, walking difficulties, facial and neck skeletal muscle tremors, especially sympathetic hyperfunction. on receptor stimulation can inhibit lymphocyte proliferation, inhibition of lymphokine and antibody formation, inhibition of induced platelet activation; clenbuterol can increase blood sugar, insulin secretion increased, causing anorexia; Tropsch can stimulate the Na / K + / ATPase of the skeletal muscle cell membrane, promote K + into the cell, the blood concentration of K + decreased, induced arrhythmia. In addition, β2 receptor excitability can cause blood lactic acid, pyruvate increased, and there ketone body, causing metabolic disorders. These pharmacological effects of clenbuterol cause adverse reactions.

Acute poisoning:   acute poisoning with palpitations, face and neck, limbs, muscle tremors, tremor can not even stand, dizziness, fatigue, the original patients with arrhythmia more likely to respond to tachycardia, ventricular premature beat, ECG ST segment depression and T wave inversion.

Hyperthyroidism and other symptoms more likely to occur:   the original sympathetic hyperactivity in patients with hypertension, coronary heart disease, hyperthyroidism, the symptoms are more likely to occur.

Lead to arrhythmia:   combined with glucocorticoids can cause hypokalemia, leading to arrhythmia.

Allergies:   repeated use will produce tolerance, weakening of the role of bronchodilation and shorten the duration. Although the residual toxicity of clenbuterol is mild, but the US FDA study shows that the application of sympathomimetic drugs or those who are allergic to prodrug, the response to clenbuterol is more serious than normal healthy individuals.