Search，Order，Antibody,ELISA Kit & Protein

Background Information：Mcl1 is an anti-apoptotic member of Bcl2 family originally isolated from the ML1 human myeloid leukemia

cell line during phorbol ester-induced differentiation along the monocyte/macrophage pathway. Mcl1 localizes to the mitochondria, interacts

with and antagonizes pro-apoptotic Bcl2 family members, and inhibits apoptosis by a number of cytotoxic stimuli. It is involved in programing

of differentiation and concomitant maintenance of viability but not of proliferation. Isoform 1 inhibits apoptosis while isoform 2 promotes it.

Expression increases early during phorbol-ester induced differentiation along the monocyte/macrophage pathway in myeloid leukemia cell lines

ML1

KeyApplications：

WB=1:100-500

ELISA=1:500-1000

IP=1:20-100

IHC-P=1:100-500

IHC-F=1:100-500

IF=1:100-500